3,4-Diamino-1,2,5-thiadiazole as potent and selective CXCR2 antagonists

A series of potent and selective 3,4-diamino-1,2,5-thiadiazoles were prepared and found to show excellent binding affinities towards CXCR2 receptor.

A novel series of potent and selective 3,4-diamino-1,2,5-thiadiazoles were prepared as CXCR2 receptor antagonists.Figure optionsDownload as PowerPoint slide