کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1376039 | 981949 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and antibacterial activity of potent heterocyclic oxazolidinones and the identification of RBx 8700
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and antibacterial activity of potent heterocyclic oxazolidinones and the identification of RBx 8700 Synthesis and antibacterial activity of potent heterocyclic oxazolidinones and the identification of RBx 8700](/preview/png/1376039.png)
چکیده انگلیسی
Several potent oxazolidinone antibacterial agents were obtained by systematic modification of the linker between the five-membered heterocycle and the piperazinyl ring of RBx 7644 (Ranbezolid, 1) and its thienyl analogue 2, leading to the identification of an expanded spectrum compound RBx 8700 (6b).
The potent broad spectrum oxazolidinone antibacterial agent RBx 8700 (6b) was obtained by systematic modification of the methylene linker of RBx 7644 (Ranbezolid, 1) and its thienyl analogue 2.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 24, 15 December 2007, Pages 6714–6719
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 24, 15 December 2007, Pages 6714–6719
نویسندگان
Sonali Rudra, Ajay Yadav, A.V.S. Raja Rao, A.S.S.V. Srinivas, Manisha Pandya, Pragya Bhateja, Tarun Mathur, Sunita Malhotra, Ashok Rattan, Mohammed Salman, Anita Mehta, Ian A. Cliffe, Biswajit Das,