Synthesis of pseudopeptides based l-tryptophan as a potential antimicrobial agent

Synthesis and biological activity of pseudopeptides based l-tryptophan are described. L-o-TrpPA being less toxic could be an effective antimicrobial broad-spectrum drug, and has a good activity against methicillin-resistant Staphylococcus aureus and fluconazole-resistant Candida spp. from clinical isolates.