Binding properties of positively charged deoxynucleic guanidine (DNG), AgTgAgTgAgT and DNG/DNA chimeras to DNA

Melting studies of mixed hexameric DNG oligonucleotide, AgTgAgTgAgT, have been evaluated. Also, DNG, AgTgAgTgAgT, have been inserted into 20-mer DNA to produce DNG/DNA chimera as a antisense agent.