کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1376352 981956 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Monoglycerides from the brown alga Sargassum sagamianum: Isolation, synthesis, and biological activity
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Monoglycerides from the brown alga Sargassum sagamianum: Isolation, synthesis, and biological activity
چکیده انگلیسی

Polyunsaturated fatty acid-derived monoglycerides were characterized from the marine brown alga Sargassum sagamianum, collected from Jeju Island, Korea. A new compound of this structural class was isolated and determined to be 1-octadecatetraenoyl glycerol, by combined spectroscopic methods. Based on the structures and bioactivity of these compounds, a series of monoglycerides were synthesized using glycerol and various fatty acids. Several compounds exhibited moderate to significant inhibition of phospholipase A2 and cyclooxygenase-2.

The isolation, synthesis, and bioactivity of fatty acid-derived monoglycerides are described.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 18, Issue 12, 15 June 2008, Pages 3589–3592
نویسندگان
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