Synthesis and structure–activity relationship of aminopyrimidine IKK2 inhibitors

The synthesis and structure–activity relationship of a novel series of aminopyrimidines are exemplified. Results of key compounds from within this series in the E-selectin reporter cell assay are also reported.

The synthesis and structure–activity relationship of a novel series of aminopyrimidines is exemplified. Results of key compounds from within this series in the E-selectin reporter cell assay are also reported.Figure optionsDownload as PowerPoint slide