A new series of pyridinyl-alkynes as antagonists of the metabotropic glutamate receptor 5 (mGluR5)

Synthesis and some structure–activity relationships for a new series of propargyl ethers as mGluR5 antagonists are reported.

Synthesis and some structure–activity relationships for a new series of propargyl ethers as mGluR5 antagonists are reported.Figure optionsDownload as PowerPoint slide