کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1376756 981964 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Macrolactin N, a new peptide deformylase inhibitor produced by Bacillus subtilis
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Macrolactin N, a new peptide deformylase inhibitor produced by Bacillus subtilis
چکیده انگلیسی

A new 24-membered ring lactone, macrolactin N, was isolated from a culture broth of Bacillus subtilis and its structure was established by various spectral analysis. Macrolactin N inhibited Staphylococcus aureus peptide deformylase with an IC50 value of 7.5 μM and also showed antibacterial activity against Escherichia coli and S. aureus.

A new 24-membered ring lactone, macrolactin N, was isolated from a culture broth of Bacillus subtilis and its structure was established by various spectral analysis. Macrolactin N inhibited Staphylococcus aureus peptide deformylase with an IC50 value of 7.5 μM.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 18, 15 September 2006, Pages 4889–4892
نویسندگان
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