کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1376844 981966 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH)
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH)
چکیده انگلیسی

Efforts to improve the properties of the well studied ketooxazole FAAH inhibitor OL-135 resulted in the discovery of a novel propylpiperidine series of FAAH inhibitors that has a modular design and superior properties to OL-135. The efficacy of one of these compounds was demonstrated in a rat spinal nerve ligation model of neuropathic pain in rats.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 18, Issue 6, 15 March 2008, Pages 2109–2113
نویسندگان
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