کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1377214 | 981974 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1 Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1](/preview/png/1377214.png)
چکیده انگلیسی
The synthesis and preliminary structure–activity relationship of a series of pyrrolidinones are described. These pyrrolidinones have been characterized as novel non-nucleoside reverse transcriptase inhibitors (NNRTIs) which are highly potent against wild-type and drug-resistant human immunodeficiency viruses (HIV-1).
N-Aryl pyrrolidinones as novel anti-HIV-1 agents is reported.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 13, 1 July 2006, Pages 3430–3433
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 13, 1 July 2006, Pages 3430–3433
نویسندگان
Baogen Wu, Kelli Kuhen, Truc Ngoc Nguyen, David Ellis, Beth Anaclerio, Xiaohui He, Kunyong Yang, Donald Karanewsky, Hong Yin, Karen Wolff, Kimberly Bieza, Jeremy Caldwell, Yun He,