کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1377437 | 981977 | 2007 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing Gram-positive and fastidious Gram-negative antibacterial activity. Part 1: Substituted pyrazoles
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
A novel series of conformationally-restricted oxazolidinones was synthesized which possess a fused pyrazole ring substituted with various alkyl, aryl and heteroaryl substituents. A number of analogs exhibited potent activity against both Gram-positive and fastidious Gram-negative organisms.
A novel series of conformationally-restricted oxazolidinones were synthesized which possess a fused pyrazole ring substituted with various alkyl, aryl and heteroaryl substituentsFigure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 16, 15 August 2007, Pages 4694–4698
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 16, 15 August 2007, Pages 4694–4698
نویسندگان
Frederick E. Boyer, J.V.N. Vara Prasad, Allison L. Choy, Louis Chupak, Michael R. Dermyer, Qizhu Ding, Michael D. Huband, Wenhua Jiao, Takushi Kaneko, Vladimir Khlebnikov, Ji-Young Kim, Manjinder S. Lall, Samarendra N. Maiti, Karina Romero, Xiujuan Wu,