Synthesis and photocytotoxic activity of new chlorin–polyamine conjugates

This paper reports the synthesis of new chlorin–polyamine conjugates designed to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested against human chronic myelogenous leukemia cells (K562) and compared to the effects of Photofrin II® and chlorin e6.

Biological tests were realized on K562 cells.Figure optionsDownload as PowerPoint slide