کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1377612 981982 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Technetium-99m-labeling and synthesis of thymidine analogs: Potential candidates for tumor imaging
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Technetium-99m-labeling and synthesis of thymidine analogs: Potential candidates for tumor imaging
چکیده انگلیسی

The technetium-99m-labeling and synthesis of a series of thymidine analogs were studied. The target molecules were obtained by using 6-hydrazinopyridine-3-carboxylic acid (HYNIC) as a bifunctional coupling agent and using N-(2-hydroxy-1,1-bis(hydroxymethyl)ethyl)glycine (tricine) and ethylenediamine-N,N′-diacetic acid (EDDA) as coligands. The effects of different spacers between thymidine analog with HYNIC on radiochemical yield were also studied.

The synthesis and labeling of a series of thymidine analogs were reported.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 12, 15 June 2007, Pages 3440–3444
نویسندگان
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