کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1377721 981986 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A practical and green approach toward synthesis of N3-substituted dihydropyrimidinones: Using Aza-Michael addition reaction catalyzed by KF/Al2O3
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
A practical and green approach toward synthesis of N3-substituted dihydropyrimidinones: Using Aza-Michael addition reaction catalyzed by KF/Al2O3
چکیده انگلیسی

A simple and efficient method for the synthesis of N3-substituted 3,4-dihydropyrimidinones by aza-Michael addition reactions of 3,4-dihydropyrimidinones to α,β-ethylenic compounds catalyzed by KF/Al2O3 is described. The advantage of this method is high regioselectivity, high purity, and the use of a cheaper, milder, and efficient catalyst for the hetero-Michael addition reaction.

A simple and efficient method for the synthesis of N3-substituted 3,4-dihydropyrimidinones by aza-Michael addition reactions of 3,4-dihydropyrimidinones to α,β-ethylenic compounds catalyzed by KF/Al2O3 is described.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 17, 1 September 2006, Pages 4592–4595
نویسندگان
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