Crystal structure, spectroscopic, and biological study of the copper(II) complex with third-generation quinolone antibiotic sparfloxacin

The neutral mononuclear copper(II) complex with the quinolone antibacterial drug sparfloxacin has been prepared and characterized with IR, UV–vis, and EPR spectroscopies and X-ray crystallography. The interaction of the complex with calf-thymus DNA has also been investigated and the antimicrobial activity has been evaluated against three different microorganisms.

The synthesis, spectroscopic study, crystal structure, and biological activity of the mononuclear Cu(II) complex with the third-generation quinolone sparfloxacin are reported.Figure optionsDownload as PowerPoint slide