O-Methylglucogalloyl esters: Synthesis and evaluation of their antimycotic activity

The two anomers of O-methyl gluco-2,3-digalloyl esters were synthesized and their antimycotic activity toward yeasts of biomedical importance was evaluated. When used at subinhibitory concentration and regardless of stereochemistry at the anomeric carbon, these compounds enhance the antimycotic activity of Amphotericin B.

Both anomers of O-methylgluco-2,3-digalloyl esters, used in subinhibitory concentration, enhance the antimycotic activity of Amphotericin B towards yeasts of biomedical relevance.Figure optionsDownload as PowerPoint slide