کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1378769 | 982009 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Rhodanine derivatives as inhibitors of JSP-1
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Rhodanine derivatives as inhibitors of JSP-1 Rhodanine derivatives as inhibitors of JSP-1](/preview/png/1378769.png)
چکیده انگلیسی
Dual-specificity phosphatases (DSPs) are a subclass within the protein tyrosine phosphatase family (PTPs). A series of rhodanine-based inhibitors was synthesized and shown to be novel, potent, and selective inhibitors against the DSP family member JNK-stimulating phosphatase-1 (JSP-1). Compounds of this class may be useful for the treatment of inflammatory and proliferative disorders.
A series of rhodanine-based inhibitors was synthesized and shown to be novel, potent, and selective inhibitors against JNK-stimulating phosphatase-1 (JSP-1), a member of the dual-specificity phosphatase family.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 15, Issue 14, 15 July 2005, Pages 3374–3379
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 15, Issue 14, 15 July 2005, Pages 3374–3379
نویسندگان
Neil S. Cutshall, Christine O’Day, Marina Prezhdo,