کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1378788 | 982009 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents](/preview/png/1378788.png)
چکیده انگلیسی
A series of 1,4-naphthoquinone derivatives were synthesized and evaluated for antibacterial and antiviral activities. The structure–activity relationships of these compounds were also studied. The results suggest that compounds 9–22 showed in vitro marked antibacterial activity. Compounds 4c and 7a showed inhibitory effect against RNA dependent RNA polymerase induced poliovirus type 2 infected HeLa cells.
The synthesis, and antibacterial and antiviral activities of 5–24 are described.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 15, Issue 14, 15 July 2005, Pages 3463–3466
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 15, Issue 14, 15 July 2005, Pages 3463–3466
نویسندگان
Vishnu K. Tandon, Dharmendra B. Yadav, Ravindra V. Singh, Meenu Vaish, Ashok K. Chaturvedi, Praveen K. Shukla,