Synthesis and screening of bicyclic carbohydrate-based compounds: A novel type of antivirals

A small library of bicyclic carbohydrate derivatives was synthesized and screened. A strong and selective activity against cytomegalovirus was found. Structure–activity relationship for this new type of antivirals is discussed.

A small library of bicyclic carbohydrate derivatives was synthesized and screened. A strong and selective activity against cytomegalovirus was found. Structure–activity relationship for this new type of antivirals is discussed.Figure optionsDownload as PowerPoint slide