کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1398155 | 1501215 | 2008 | 27 صفحه PDF | دانلود رایگان |
An exploratory chemical effort has been undertaken to develop a novel series of compounds as selective CB1 agonists. It is hoped that compounds of this type will have clinical utility in pain control, and cerebral ischaemia following stroke or traumatic head injury.We report here medicinal chemistry studies directed towards the investigation of a series of 1-substituted-indole-3-oxadiazoles as potential CB1 agonists.
We report here medicinal chemistry studies directed towards the investigation of a series of aminoalkylindole compounds of the formula 1, which were designed and synthesized as selective CB1 agonists. It is hoped that novel compounds of this type will have clinical utility in pain control, and cerebral ischaemia following stroke or traumatic head injury.Figure optionsDownload as PowerPoint slide
Journal: European Journal of Medicinal Chemistry - Volume 43, Issue 3, March 2008, Pages 513–539