کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1399253 | 1501156 | 2013 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Alkyl esters of gallic acid as anticancer agents: A review Alkyl esters of gallic acid as anticancer agents: A review](/preview/png/1399253.png)
The current review presents the antitumoral properties of gallic acid and its ester derivatives. Numerous studies have indicated that the alkyl esters are more effective against tumor cell lines than gallic acid, and that this activity is related to their hydrophobic moiety. All related studies have shown that the antitumor activity is interconnected to the induction of apoptosis by different mechanisms and it depends on the cell type. The results presented in this review may help to emphasize that these compounds could be promising as a new alternative for the treatment of cancer, either alone or in combination with other antitumor drugs to potentiate their effects.
Figure optionsDownload as PowerPoint slideHighlights
► The antitumor activity of gallates is interconnected to the induction of apoptosis.
► The cell death is related to different mechanisms and it depends on the cell type.
► The gallates are potential inhibitors of metastasis.
Journal: European Journal of Medicinal Chemistry - Volume 60, February 2013, Pages 233–239