کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1428209 1509172 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Silver release and antimicrobial properties of PMMA films doped with silver ions, nano-particles and complexes
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
Silver release and antimicrobial properties of PMMA films doped with silver ions, nano-particles and complexes
چکیده انگلیسی


• PMMA thin films doped with silver ions, nanoparticles (AgNPs) and silver–imidazole helical complexes (AgIm) were studied.
• Silver release from doped polymer films and its biological activity were estimated.
• Antimicrobial properties of doped polymer films were also studied.
• Ag ions doped films showed the strongest antimicrobial activity, which quickly disappeared.
• AgIm and AgNPs doped films showed more stable antimicrobial properties.
• AgIm complexes conserve their structure after addition into polymer and after leaching.

Materials prepared on the base of bioactive silver compounds have become more and more popular due to low microbial resistance to silver. In the present work, the efficiency of polymethylmethacrylate (PMMA) thin films doped with silver ions, nanoparticles and silver–imidazole polymer complex was studied by a combination of AAS, XPS and AFM techniques. The biological activities of the proposed materials were discussed in view of the rate of silver releasing from the polymer matrix. Concentrations of Ag active form were estimated by its ability to interact with l-cysteine using electronic circular dichroism spectroscopy. Rates of the released silver were compared with the biological activity in dependence on the form of embedded silver. Antimicrobial properties of doped polymer films were studied using two bacterial strains: Staphylococcus epidermidis and Escherichia coli. It was found that PMMA films doped with Ag+ had greater activity than those doped with nanoparticles and silver–imidazole polymeric complexes. However, the antimicrobial efficiency of Ag+ doped films was only short-term. Contrary, the antimicrobial activity of silver–imidazole/PMMA films increased in time of sample soaking.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 49, 1 April 2015, Pages 534–540
نویسندگان
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