کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1428495 1509173 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The influence of silanisation on the mechanical and degradation behaviour of PLGA/HA composites
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
The influence of silanisation on the mechanical and degradation behaviour of PLGA/HA composites
چکیده انگلیسی


• The influence of silanisation on the properties of PLGA/HA composites was studied.
• Mechanical properties and degradation profile were investigated.
• Three different silanes were used in the study.
• The influence of various parameters on silanisation was examined.
• Silanisation was found to influence the plastic mechanical properties.

This study investigates the influence of silanisation on the mechanical and degradation behaviour of PLGA/HA composites. Three different silanes (mercaptopropyl trimethoxy silane (MPTMS), aminopropyl trimethoxy silane (APTMS) and aminopropyltriethoxy silane (APTES)) were applied to HA substrates in order to study the effect of head group (which binds to the polymer) and tail group (which binds to the surface hydroxyl groups in HA). A composite of hydroxyapatite (HA) and poly(d,l lactide-co-glycolide (50:50)) (PLGA) was investigated.The influence of concentration, the reaction time, drying temperature and substrate surface on silanisation was examined. TGA was used to detect the degree of silanisation.HA with MPTMS (1 wt.% MPTMS with reaction time of 1 h) was used as filler in PLGA-30 wt.% HA composites for an in-vitro degradation study carried out in PBS. In addition, the mechanical properties of the composites were studied.Silanisation affects the properties of the composite by improving the bonding at the interface and hence it was found to influence the plastic mechanical properties rather than the elastic mechanical properties or the degradation profile of the composite.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 48, 1 March 2015, Pages 642–650
نویسندگان
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