Biomimetic synthesis of micrometer spherical hydroxyapatite with β-cyclodextrin as template

Spherical hydroxyapatite (HA) crystals were prepared successfully with β-cyclodextrin (β-CD) as template by biomimetic method. Their properties were characterized by X-ray powder diffraction (XRD), Fourier transform infrared spectroscope (FTIR), thermogravimetric analyzer (TG), and scanning electron microscope (SEM). The results show that the concentration of β-CD have a significant effect on the morphology of HA crystals. Spherical HA crystals with the diameter of 1.0–3.0 μm can be obtained in the presence of 1.5% β-CD. The obtained crystals are the composites of HA/β-CD. This is a result of the interaction between HA and β-CD.