کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1430168 | 987196 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of protein incorporation on calcium phosphate coating
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Effects of protein incorporation on calcium phosphate coating Effects of protein incorporation on calcium phosphate coating](/preview/png/1430168.png)
چکیده انگلیسی
The incorporation of protein molecules was shown to affect the properties of Ca-P coatings in terms of morphology, composition and crystallinity. Both proteins seem to inhibit in some extent and/or retard the growth of Ca-P nuclei at 0.5 and 5 mg/mL concentrations. FTIR analyses revealed the presence of phosphate and carbonate groups, confirming the formation of a Ca-P layer. The characteristic groups of protein molecules were also detected on the IR spectra, which indicate the efficient incorporation of the proteins into the coatings. When α-amylase was added to the SBF solution the production of reducing sugars was detected, proving the retention of enzyme activity. These results suggest the carrier potential of Ca-P coatings for the sustained delivery of other biologically active proteins and consequently with a strong potential for inducing bone tissue regeneration.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 29, Issue 3, 30 April 2009, Pages 913-918
Journal: Materials Science and Engineering: C - Volume 29, Issue 3, 30 April 2009, Pages 913-918
نویسندگان
I.B. Leonor, C.M. Alves, H.S. Azevedo, R.L. Reis,