کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1430452 | 987203 | 2009 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Preparation of chitosan–sodium alginate microcapsules containing ZnS nanoparticles and its effect on the drug release
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
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چکیده انگلیسی
Chitosan–sodium alginate microcapsules were prepared in the presence of ZnS nanoparticles via the W/O/W emulsification solvent-evaporation method. Microscopy showed that the microsphere was about 150 nm and by the absorption spectra, ZnS nanoparticles incorporated was 4 nm. Aspirin was chosen to investigate the effect of microcapsules on the drug release. It reveals that comparing with the microsphere without nanoparticles, the release speed of microsphere containing ZnS nanoparticles is significantly decreased from complete release at 10 h to 50% release by 50 h. The data of release kinetics for the microcapsules can be well fitted by the classic Higuchi model.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 29, Issue 7, 31 August 2009, Pages 2250–2253
Journal: Materials Science and Engineering: C - Volume 29, Issue 7, 31 August 2009, Pages 2250–2253
نویسندگان
Zhulai Li, Peng Chen, Xiuzhi Xu, Xiao Ye, Jin Wang,