کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1430702 | 987208 | 2009 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Preparation and characterization of 2,3-dialdehyde bacterial cellulose for potential biodegradable tissue engineering scaffolds Preparation and characterization of 2,3-dialdehyde bacterial cellulose for potential biodegradable tissue engineering scaffolds](/preview/png/1430702.png)
Bacterial cellulose (BC) is suitable for applications as scaffolds in tissue engineering due to its unique properties. However, BC is not enzymatically degradable in vivo and this has become an essential limiting factor in its potential applications. In this work, BC was modified by periodate oxidation to give rise to a biodegradable 2,3-dialdehyde bacterial cellulose (DABC). After characterization by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), attenuated total reflectance–Fourier transform infrared (ATR–FTIR) spectroscopy, thin-film X-ray diffractometry (XRD) and X-ray photoelectron spectroscopy (XPS), we demonstrated that the modified DABC nano-network was able to degrade into porous scaffold with micro-sized pores in water, phosphate buffered saline (PBS) and the simulated body fluid (SBF). The degradation process began from the oxidized amorphous part of the network and concurrently hydroxyapatite formed on the scaffold surface during the process in SBF. Our data also demonstrated that the tensile mechanical properties of the DABC nano-network were suitable for its use in tissue engineering scaffolds.
Journal: Materials Science and Engineering: C - Volume 29, Issue 5, 1 June 2009, Pages 1635–1642