کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1431142 987221 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Titanium oxide nanotubes with controlled morphology for enhanced bone growth
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
Titanium oxide nanotubes with controlled morphology for enhanced bone growth
چکیده انگلیسی

An array of vertically aligned titanium oxide nanotubes was grown on the surface of titanium substrate by anodization. A chemical treatment with NaOH solution to make them more bioactive with a formation of nanoscale sodium titanate structure. The presence of such treated TiO2 nanotubes significantly accelerated the kinetics of hydroxyapatite growth by a factor of as much as 7. The adhesion/growth of osteoblast cells is also significantly accelerated by the topography of the TiO2 nanotubes with the filopodia of the growing cells actually going into the nanotube pores, producing a locked-in cell structure. The number of the adhered cells on the TiO2 nanotubes increases by as much ∼400% as compared to the Ti metal, most likely caused by the pronounced topological feature, significantly increased surface area, as well as the in-between-nanotube pathways for fluid. Such an array of TiO2 nanotubes well adherent on Ti implant surface can be useful for accelerated bone growth in orthopaedic/dental applications.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 26, Issue 8, September 2006, Pages 1301–1306
نویسندگان
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