Synthetic hydroxyapatite in pharmaceutical applications

Synthetic hydroxyapatite plays a key role in implantology, stomatology, and regenerative medicine. Thanks to its non-toxicity and biocompatibility with bone and mineralised dental tissues, it has found application as a bone substitute. The fact that porous granules and scaffolds can be made out of nanocrystalline hydroxyapatite, and that it has a high loading capacity, means that it can be used in pharmaceutical science as a carrier for drugs or a system for controlled drug release. The aim of this study is to present current trends in research on synthetic hydroxyapatite as a carrier for drugs used in the local treatment of bone tissue disorders (multifunction implants) and poorly soluble drugs, including those with limited bioavailability.