کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1463448 | 989647 | 2013 | 13 صفحه PDF | دانلود رایگان |
The corrosion behavior of magnesium and its alloys in the electrolytic physiological environment is extremely poor; this imposes a limitation for their use in orthopedic applications. In the present study, the effect of spray coating AZ31 magnesium alloy with membrane films of pristine and hydroxyapatite-doped poly(lactic acid) on corrosion behavior and bioactivity is investigated. Polymer concentration was found to have a strong impact on the pore size of the coating layer. However, addition of HAp NPs distinctly stimulated the precipitation of an apatite-like compound upon soaking the samples in a simulated body fluid (SBF). Magnesium coated samples revealed three orders of magnitude less corrosion compared to the naked samples, which indicates a stable electrochemical corrosion resistance. During a 15 days in-vitro test, pH variation, weight loss, and bending strength were lower for the coated samples (with average values of 8.5%, 7.2% and 10%, respectively) than the control sample (10.5%, 15.5%, and 25%, respectively). Moreover, the coated samples showed good bending strength characteristics. Cytocompatibility studies on MC3T3 cells revealed a continuous increase in cell growth with the coated samples. Overall, the suggested strategy might open a new avenue to widen utilization of Mg alloys as implant materials for orthopedic applications.
Journal: Ceramics International - Volume 39, Issue 1, January 2013, Pages 183–195