کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1475060 | 991108 | 2012 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Response of osteoblast-like MG63 cells to TiO2 layer prepared by micro-arc oxidation and electric polarization Response of osteoblast-like MG63 cells to TiO2 layer prepared by micro-arc oxidation and electric polarization](/preview/png/1475060.png)
Micro-arc oxidation (MAO) is one of the useful surface modifications of titanium implants to improve bioactivity. Also, electric polarization treatment enhances bioactivity of calcium phosphate. The aim of this study was to evaluate the effect of the combination of two surface modifications, micro-arc oxidation (MAO) with electric polarization, on the behavior of osteoblast-like osteosarcoma MG63 cells. MAO-treated materials had a surface geometry that was favored by MG63 cells as determined using scanning electron microscopy and X-ray diffraction; additionally, electric polarization induced surface electric fields, which were measured using thermally stimulated depolarization currents. The results of assays to study cell–material interactions suggest that these two approaches could regulate cell attachment, spreading, proliferation, and differentiation without the addition of other reagents. This new surface modification processes produce materials with a good surface geometry, generate surface electric fields and enhance the osteopromotive ability of osteoblasts.
Journal: Journal of the European Ceramic Society - Volume 32, Issue 11, August 2012, Pages 2647–2652