In vivo non-mechanical scanning grating-generated optical coherence tomography using an InGaAs digital camera

We demonstrated in vivo cross-sectional imaging of human fingers by non-mechanical scanning optical coherence tomography (OCT), using a diffracted light as the reference beam and a linear illumination beam at a center wavelength of 1.3 μm for deeper penetration into biological tissues. By applying the three-step phase-shifting method, our system can measure OCT images at 10 frames/s with a sensitivity of 90 dB for a 2.45 × 4.80 mm (axial × lateral) measurement range using an InGaAs digital camera (320 × 256 pixels).