کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1631009 | 1006615 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Formulation and Evaluation of Genistein – A Novel Isoflavone Loaded Chitosan and Eudragit® Nanoparticles for Cancer Therapy
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
فلزات و آلیاژها
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چکیده انگلیسی
Cancer becomes a leading cause of death around the world. The goal of the present investigation was to formulate and evaluate chitosan and Eudragit® nanoparticles of Genistein, the predominant isoflavone found in soy products for cancer therapy. Nanoparticles of Genistein were prepared by Emulsion droplet coalescence method using chitosan, Eudragit® S100, liquid paraffin and Tween-20. Drug entrapment and particle size of optimized batch of the genistein nanoparticles were approximately 80.26 ± 0.68% and 79.32 ± 1.09 respectively. The delivery of Genistein loaded Chitosan and Eudragit S100 loaded polymeric nanoparticles is feasible approach to treat cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Today: Proceedings - Volume 2, Issue 9, Part A, 2015, Pages 4477-4482
Journal: Materials Today: Proceedings - Volume 2, Issue 9, Part A, 2015, Pages 4477-4482