کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
1641057 1517205 2016 4 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
Cations influence the cross-linking of hydrogels made of recombinant, polyanionic spider silk proteins
ترجمه فارسی عنوان
کاتیونها بر پیوند متقابل هیدروژل های ساخته شده از پروتئین های ابریشم عنکبوتی نوترکیب و پلیانیونی اثر می گذارند
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد فناوری نانو (نانو تکنولوژی)
چکیده انگلیسی


• Characterized spider silk bioinks in the presence of Dulbecco's Modified Eagle Medium.
• Examined effects of cations on the behavior of spider silk-based bioinks.
• Determined possibility of ionic crosslinking in charged, spider silk-based bioinks.

Hydrogels made of polyanionic recombinant spider silk proteins (spidroins) were prepared either in the presence or the absence of Dulbecco's Modified Eagle Medium (DMEM). Mono- and divalent cations present in DMEM severely affected the self-assembly process of the spidroins. Although the addition of DMEM had no apparent effect on secondary structure formation, there was a significant effect on the kinetics as well as on the hydrogel network; in the presence of DMEM, gelation occurred more rapidly. Additionally, the hydrogels were stiffer; however, the hydrogels were still shear-thinning. In summary, it can be concluded that there is a significant impact of ionic cross-linking on recombinant spidroin-based hydrogels.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Letters - Volume 183, 15 November 2016, Pages 101–104
نویسندگان
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