Biocompatibility of electrospun graphene oxide–poly(ε-caprolactone) fibrous scaffolds with human cord blood mesenchymal stem cells derived skeletal myoblast

• Electrospun graphene oxide (GO)–poly(ε-caprolactone) (PCL) composite fibrous scaffolds prepared.
• Biocompatibility of GO–PCL fibrous scaffolds studied.
• Human cord blood mesenchymal stem cell derived myoblasts used for the biocompatibility study of the scaffolds.
• First observation of myoblast adhesion and differentiation onto these GO–PCL scaffolds.

Biocompatibility of electrospun graphene oxide (GO)–poly (ε-caprolactone)-(PCL) composite fibrous scaffolds has been investigated using skeletal muscle cells obtained from human umbilical cord blood (UCB) derived mesenchymal stem cells (CB-hMSCs). Such CB-hMSCs derived human skeletal muscle cells (CB-hSkMCs) adhered, proliferated and formed myotubes when cultured on GO–PCL fibrous scaffold suitable for skeletal muscle tissue engineering applications.