Nanohydroxyapatite prepared from non-toxic organic Ca2+ compounds by precipitation in aqueous solution

Nanocrystalline hydroxyapatites were prepared by the precipitation method using a water soluble Ca2+ organic compounds and (NH4)2HPO4. The fine nanohydroxyapatites had spherical, needle-like or mixed morphology and specific areas around 150 m2/g. The nanocrystalline powders differed by thermal stability and they were transformed to bi- or three-phasic systems with hydroxyapatite, βTCP and αTCP phases after annealing at 1000 °C.

► Preparation of nanohydroxyapatite without utilisation of toxic organic substances.
► No additional thermal treatment is needed for removing undesirable residues.
► Organic residues from ligands of Ca2+ compounds are feasible for living organism.