کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1759778 | 1019296 | 2008 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Therapeutic opportunities in biological responses of ultrasound Therapeutic opportunities in biological responses of ultrasound](/preview/png/1759778.png)
The therapeutic benefits of several existing ultrasound-based therapies such as facilitated drug delivery, tumor ablation and thrombolysis derive largely from physical or mechanical effects. In contrast, ultrasound can also trigger various time-dependent biochemical responses in the exposed biological milieu. Several biological responses to ultrasound exposure have been previously described in the literature but only a handful of these provide therapeutic opportunities. These include the use of ultrasound for healing of soft tissues and bones, the use of ultrasound for inducing non-necrotic tumor atrophy as well as for potentiation of chemotherapeutic drugs, activation of the immune system, angiogenesis and suppression of phagocytosis. A review of these therapeutic opportunities is presented with particular emphasis on their mechanisms. Overall, this review presents the increasing importance of ultrasound’s role as a biological sensitizer enabling novel therapeutic strategies.
Journal: Ultrasonics - Volume 48, Issue 4, August 2008, Pages 271–278