Ratiometric double channel borondipyrromethene based chemodosimeter for the selective detection of nerve agent mimics

• A new OFF–ON chemodosimeter for the colourimetric and fluorescent detection of nerve agent mimics has been synthesized.
• The probe includes a 2-(2-(dimethylamino)phenyl)ethanol as receptor unit and a BODIPY dye as both fluorescent and chromogenic signalling unit.
• The efficiency of the system has been evaluated in solution and also in the gas phase using solid supports.
• Low limit of detection have been determined.
• Easily observable responses through the two different optical channels has been observed.

A new chromo-fluorogenic probe based on the borondipyrromethene dye has been synthesized. The dye has been attached to a sensing unit for the diethylcyanophosphonate and di-isopropylfluorophosphate detection. The new probe has been fully characterized, and its optical properties in front of these simulants have been evaluated. No interference from other organo-phosphorous or other common contaminants compounds has been observed in the detection conditions. A portable kit has been developed and tested to demonstrate its practical application in real-time monitoring not only in solution but also in gas phase.

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