کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
176467 458943 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Design and synthesis of water-soluble polyaminated chlorins and bacteriochlorins – With near-infrared absorption
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Design and synthesis of water-soluble polyaminated chlorins and bacteriochlorins – With near-infrared absorption
چکیده انگلیسی

To enhance the solubility of two new photosensitizers (PS), obtained from natural products (Spirulina maxima and Rhodobacter sphaeroides), derivatization of purpurin-18 1 and bacteriopurpurin-18 3 with a cationic polymer: PEI (polyethylenimine) led to the production of polyaminated chlorins 5–6 and bacteriochlorins 7–8, respectively. These new water-soluble photosensitizers have been designed for their potential use in PDT: they are endowed with facilitated accumulation into cancer cells, and their respective Q bands, in the near-infrared region of the visible spectrum, span over the deepest therapeutic window of human tissues.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Dyes and Pigments - Volume 98, Issue 3, September 2013, Pages 609–614
نویسندگان
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