Anisotropy and charge effect in collisions of ions with biomolecules

Charge transfer dynamics induced by collision of carbon ions with biological targets has been investigated theoretically by means of ab-initio quantum chemistry molecular methods. The series of pyrimidine nucleobases, thymine, uracil and 5-halouracil with similar skeleton and different substituents have been considered. The charge effect between C6+ and C4+ carbon ions is analyzed as well as the anisotropy of the electron exchange process.

► Charge transfer in ion–biomolecule collisions.
► Ab-initio calculations of potential energy curves and couplings.
► Anisotropy and charge effect.
► Interest with regard to action of radiations on the biological medium.