High specific activity 61Cu via 64Zn(p,α)61Cu reaction at low proton energies

► Routine production of high SA 61Cu via the 64Zn(p,α)61Cu. ► Two different fast and hot cell compatible methods for separation of Cu-radioisotopes generated from Zn-targets. ► Specific activity determination of 61Cu generated from Zn-targets. ► Optimized 64Zn recycling and purification.