کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1876361 | 1042004 | 2012 | 5 صفحه PDF | دانلود رایگان |
Successful use of electrochemical method to concentrate 99mTc obtained from a zirconium molybdate (Zr99Mo) gel generator is reported. The process consists of electrodeposition of the 99mTc in an oxalate bath on a small platinum electrode followed by recovery of 99mTc in a small volume of normal saline. The overall recovery of 99mTc was >90% with >99.99% radionuclidic purity and >99% radiochemical purity. The compatibility of the product in the preparation of 99mTc labeled formulations such as 99mTc-DMSA and 99mTc-EC was found to be satisfactory in terms of high labeling yields (>98%).
► Utility of electrochemical technique to concentrate 99mTc obtained from an expired Zr99Mo gel generator.
► Optimization of experimental conditions for quantitative deposition of 99mTc.
► Evaluation of quality features of the concentrated 99mTcO4− solution for radiopharmaceutical applications.
Journal: Applied Radiation and Isotopes - Volume 70, Issue 2, February 2012, Pages 375–379