کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1876576 | 1042022 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Questioning the value of 99mTc-HYNIC-annexin V based response monitoring after docetaxel treatment in a mouse model for hereditary breast cancer
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Questioning the value of 99mTc-HYNIC-annexin V based response monitoring after docetaxel treatment in a mouse model for hereditary breast cancer Questioning the value of 99mTc-HYNIC-annexin V based response monitoring after docetaxel treatment in a mouse model for hereditary breast cancer](/preview/png/1876576.png)
چکیده انگلیسی
Annexin V imaging is suggested to provide a good indication of cancer treatment efficacy. To study the accuracy of 99mTc-AnxV imaging, we monitored chemo-sensitive and chemo-resistant tumors in a mouse breast cancer model after treatment with docetaxel. Sensitive tumors showed a slight peak in 99mTc-AnxV uptake one day post-treatment, while uptake in resistant tumors remained constant. In contrast to immunohistochemical analysis, 99mTc-AnxV imaging could not be used to predict tumor response, due to large variation between animals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 69, Issue 4, April 2011, Pages 656–662
Journal: Applied Radiation and Isotopes - Volume 69, Issue 4, April 2011, Pages 656–662
نویسندگان
Chantal A.C. Beekman, Tessa Buckle, Anne C. van Leeuwen, Renato A. Valdés Olmos, Marcel Verheij, Sven Rottenberg, Fijs W.B. van Leeuwen,