کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1876739 | 1042031 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Imaging of regional metabolic activity by 18F-FDG/PET in rats with transient cerebral ischemia
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موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
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چکیده انگلیسی
Changes in regional metabolic activities induced by middle cerebral artery occlusion (MCAO) can influence patient outcome. Our aim was to demonstrate in a rat model that 18F-FDG with positron emission tomography (PET) imaging is a quantitative, reproducible approach for identifying acute and sub-acute metabolic variations in infarct regions. We found that imaging with 18F-FDG/PET enabled detection and quantification of ischemia-induced metabolic deficits and provided a sensitive and reliable means of assessing cerebral ischemic lesions compared with conventional neurological scoring systems in rodents.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 67, Issue 10, October 2009, Pages 1743–1747
Journal: Applied Radiation and Isotopes - Volume 67, Issue 10, October 2009, Pages 1743–1747
نویسندگان
Ying-Kai Fu, Chia-Jung Chang, Kuan-Yin Chen, Li-Chung Hwang, Kuo-Hung Wu, Kang-Wei Chang, Meei-Ling Jan, Chia-Chieh Chen, Chih-Hsien Chang,