کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1876760 | 1042031 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Development of a modular system for the synthesis of PET [11C]labelled radiopharmaceuticals
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Development of a modular system for the synthesis of PET [11C]labelled radiopharmaceuticals Development of a modular system for the synthesis of PET [11C]labelled radiopharmaceuticals](/preview/png/1876760.png)
چکیده انگلیسی
[11C]labelled radiopharmaceuticals as N-[11C]methyl-choline ([11C]choline), l-(S-methyl-[11C])methionine ([11C]methionine) and [11C]acetate have gained increasing importance in clinical PET and for the routine production of these radiopharmaceuticals, simple and reliable modules are needed to produce clinically relevant radioactivity. On the other hand, flexible devices are needed not only for the routine synthesis but also for more complex applications as the development of new tracers. The aim of this work was the adaptation of an Eckert Ziegler modular system for easy routine synthesis of [11C]choline, [11C]methionine and [11C]acetate using components that account for straightforward scaling up and upgrades.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 67, Issue 10, October 2009, Pages 1869–1873
Journal: Applied Radiation and Isotopes - Volume 67, Issue 10, October 2009, Pages 1869–1873
نویسندگان
Stefano Boschi, Filippo Lodi, Gianfranco Cicoria, Jorge Raul Ledesma, Roger Knopp, Anna Rizzello, Donato Di Pierro, Silvia Trespidi, Mario Marengo,