کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1877762 | 1042239 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Studies for the application of boron neutron capture therapy to the treatment of differentiated thyroid cancer
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موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
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چکیده انگلیسی
The aim of these studies was to evaluate the possibility of treating differentiated thyroid cancer by BNCT. These carcinomas are well controlled with surgery followed by therapy with 131I; however, some patients do not respond to this treatment. BPA uptake was analyzed both in vitro and in nude mice implanted with cell lines of differentiated thyroid carcinoma. The boron intracellular concentration in the different cell lines and the biodistribution studies showed the selectivity of the BPA uptake by this kind of tumor.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 69, Issue 12, December 2011, Pages 1752–1755
Journal: Applied Radiation and Isotopes - Volume 69, Issue 12, December 2011, Pages 1752–1755
نویسندگان
A. Dagrosa, M. Carpano, M. Perona, L. Thomasz, S. Nievas, R. Cabrini, G. Juvenal, M. Pisarev,