کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1877764 | 1042239 | 2011 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Sodium mercaptoundecahydro-closo-dodecaborate (BSH), a boron carrier that merits more attention
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موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Boron neutron capture therapy relies on the preferential delivery of a 10B-compound to tumor cells. The BSH-biodistribution was investigated in nu/nu mice and human patients. The boron concentration was measured with prompt gamma ray spectroscopy. BSH accumulates to a very low extent not only in brain, but also in fat tissue, bone and muscle, which makes BSH an interesting drug not only for brain lesions but also for tumors located at the extremities. The differential uptake in different organs indicates a complex mechanism.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 69, Issue 12, December 2011, Pages 1760–1764
Journal: Applied Radiation and Isotopes - Volume 69, Issue 12, December 2011, Pages 1760–1764
نویسندگان
Andrea Wittig, Finn Stecher-Rasmussen, Ralf A. Hilger, Jürgen Rassow, Pierluigi Mauri, Wolfgang Sauerwein,