کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1878052 | 1042270 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and analysis of 2-[211At]-l-phenylalanine and 4-[211At]-l-phenylalanine and their uptake in human glioma cell cultures in-vitro
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and analysis of 2-[211At]-l-phenylalanine and 4-[211At]-l-phenylalanine and their uptake in human glioma cell cultures in-vitro Synthesis and analysis of 2-[211At]-l-phenylalanine and 4-[211At]-l-phenylalanine and their uptake in human glioma cell cultures in-vitro](/preview/png/1878052.png)
چکیده انگلیسی
2-[211At]-l-phenylalanine and 4-[211At]-l-phenylalanine were prepared from the corresponding iodo and bromo derivatives using the Cu+-assisted nucleophilic exchange. 4-[211At]-l-phenylalanine was additionally prepared by destannylation of the BOC-derivatized 4-tributylstannyl-l-phenylalanine. Radiochemical yields of 2-[211At]-l-phenylalanine and 4-[211At]-l-phenylalanine by nucleophilic exchange were 52–74% and 65–85%. Radiochemical yield of 4-[211At]-l-phenylalanine by electrophilic destannylation was 35–50%. HPLC sequence analysis showed that 2-[211At]-l-phenylalanine followed the halogen sequence (F
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 68, Issue 6, June 2010, Pages 1060–1065
Journal: Applied Radiation and Isotopes - Volume 68, Issue 6, June 2010, Pages 1060–1065
نویسندگان
Geerd J. Meyer, Almut Walte, Siva R. Sriyapureddy, Michaela Grote, Doris Krull, Zekiye Korkmaz, Wolfram H. Knapp,