Development of a new design 125I-brachytherapy seed for its application in the treatment of eye and prostate cancer

Palladium coated silver beads of 0.5 mm (∅) were used to adsorb 125I and encapsulated inside a titanium capsule by Nd:YAG laser, for use as a brachytherapy source. Experimental conditions were optimized for maximum adsorption of 125I and uniformity of radioactivity was ascertained. Leachability of 125I was found to be<0.01%. The dose rate constant of the new source was estimated to be 1.045 cGy h−1 U−1. This newly developed source could be an alternative to other 125I sources.