Dosimetric aspects of 166Ho brachytherapy biodegradable glass seed

► A beta emitter bioglass Ho-166 seed has been proposed for treating small HCC tumors. ► The MCNP5 code was used to investigate dose distributions around the seed. ► The dosimetric parameters recommended by the AAPM Task Group 60 (TG-60) were calculated. ► The short range of the beta particles limits damage to the normal tissues.